Okay, but systemd can't teleport data. This could let you carry your home directory on a thumbdrive or such, but it's not a synchronization daemon. It kinda sounds like you just want syncthing or the like?
Roaming home directories are a goal of this project. It can work via home on a usb stick. I'm not sure how/if it works with network shares and usb both - something I want as I have several computers on my desk and lahtops I use for travel.
It would also work over NFS, which could have value.
My interest is actually in the opposite direction; I want a single machine with all home directories on its own internal hard disk, but where each user encrypts their home directory separately. That's doable other ways, but homed could be a nice way to do it that works out of the box.