True, and even CRTs had the issue that if you set a resolution that created interference in the shadow mask it would look like crap. There was a always a 'best' resolution to a CRT even if it was forgiving in terms of different settings.
Given the 'free' GPU we get with machines these days (and by free I mean its always included) it seems reasonable to use its oversampling anti-aliasing feature for desktop display. I'm not sure why you wouldn't do that unless it was some sort of power issue.
The power issue is hugely significant. Using a GPU kills battery life, which is why laptops now have two GPUs -- a low-power basic GPU and a switchable high-power GPU
Given the 'free' GPU we get with machines these days (and by free I mean its always included) it seems reasonable to use its oversampling anti-aliasing feature for desktop display. I'm not sure why you wouldn't do that unless it was some sort of power issue.