Notice that all the replacements for those keys in the Mac world require a two-key combo. Two keys from two separate hands in most cases (fn + arrows accounting for 4 of them and fn+delete being the fifth).

That means you can't poke at it with one hand while walking past with a cup of coffee, use it while keeping a mouse in one hand, or otherwise interact with it casually. It's a small annoyance, but one that simply doesn't exist in the Windows experience.

All other things being roughly equal between those two worlds, I find myself using the old XP box in favor of the Mac most of the time. Mostly for the reason the grandparent mentions.