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I personally feel you're being overly optimistic. Genes, markers and all of that might seem like high tech medicine, but to the extent that I know there has not been much progress on that front, although it's been hyped a lot, and gets a lot of media coverage.


I don't think it has to be about being "high tech medicine".

In this case, the existing documentation of such things combined with the events in the GP's own medical history have been fed into a machine that can identify patterns that a human doctor should have, but for whatever reason has not, identified.

I think the potential ramifications for this are huge.


Even if this is right, something about this reply feels like it’s missing the magic of the moment we’re in. No empathy,


Indeed HLA-B27 only has a partial correlation with diseases such as AxSpa.

"... about 7 percent of Americans are positive for HLA-B27 but only 5 to 10 percent of people with a positive HLA-B27 will have AS" https://creakyjoints.org/about-arthritis/axial-spondyloarthr...


5 to 10 percent in the general population. If you already have many of the symptoms, but those symptoms are not specific enough to distinguish between similar autoimmune diseases, then the prior is widely different so a test like this becomes much more relevant.


What was the intent of this message?




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