If you don't know, insulin signals a process for sequestering sugars through glycogenesis.
Stevia and Glucose groups both increased plasma insulin. Contrasted with Saccharine and Sucralose which, the authors suggest, blunted insulin release and thus increased blood sugar. They cite a paper indicating that combined NNS and caloric sweeteners increase the insulin response compared with a NNS itself.
So... both..? It's a disproportion. NNS should have negligible impact on blood sugar to be called "inert", either when paired or when not, regardless of whether glucose is present or not. Addition is changing the whole formula. They're saying it's fucking up the signal interpretation. At least that's what I've put together.
thing effect on plasma insulin gut result
glucose baseline increase standard
g+sucralose increase less than baseline altered
g+stevia baseline increase altered
g+aspartame baseline increase altered
So since there was lower than baseline increase in the g+sucralose group, we can conclude that the sucralose is blunting the response that the glucose would have caused.
So, in this context, that means we got increased blood sugar because of the lower plasma insulin? Okay. I think I understand now.
Stevia and Glucose groups both increased plasma insulin. Contrasted with Saccharine and Sucralose which, the authors suggest, blunted insulin release and thus increased blood sugar. They cite a paper indicating that combined NNS and caloric sweeteners increase the insulin response compared with a NNS itself.
So... both..? It's a disproportion. NNS should have negligible impact on blood sugar to be called "inert", either when paired or when not, regardless of whether glucose is present or not. Addition is changing the whole formula. They're saying it's fucking up the signal interpretation. At least that's what I've put together.