IPSec is pretty much the standard interop still - pretty much everything talks it Cisco, Juniper, pfSense, Fortinet, etc. You name it I’d be surprised if it didn’t have support.
I’d love to see wireguard implemented in the networking world, but I think it may take some time to get there :/
Can I ask, do you perform updates and maintenance on these boxes? How do they perform in terms of throughput with openvpn?