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coronaviruses are also RNA viruses, fwiw


It’s a different kind. HIV is a retrovirus in that RNA is reverse transcribed into DNA. Coronavirus transcribes to RNA directly.


And macadamia nuts are named after a different John Macadam (beyond similar names, nothing indicates a close blood relationship)

https://en.wikipedia.org/wiki/John_Macadam


Didn't you know that everyone on HN bakes their own bread?


We are a board for a company whose stated mission is to develop AI tools to better serve the needs of humanity. The CEO has secretly piloted the company towards alternate goals of profit. We fired him on Friday but think it was a mistake. Who knows. Anyways, how can we rehire him?

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Rehiring a CEO whom you've recently fired is a delicate process, both from a legal and business standpoint. Here's a general approach you might consider:

1. *Board Meeting*: Convene a board meeting to discuss the decision to rehire the CEO. This should involve all key stakeholders to ensure transparency and agreement.

2. *Legal Considerations*: Consult with legal counsel to understand any legal implications or contractual issues arising from the initial termination and potential rehiring.

3. *Negotiation and Terms*: If the board agrees to proceed, you'll need to negotiate new terms with the CEO. This might include discussions about the future direction of the company, salary, and any conditions related to the rehire.

4. *Addressing the Underlying Issues*: It's important to address the reasons that led to the initial firing. This might involve setting clearer goals aligned with the company's mission, establishing better oversight, or implementing checks and balances.

5. *Communication*: Once an agreement is reached, communicate the decision to rehire the CEO to your employees, stakeholders, and possibly the public, depending on the nature of your company. This communication should be clear about the reasons for the reversal and the future direction of the company.

6. *Monitoring and Evaluation*: Finally, set up a system for regularly evaluating the CEO's performance against the company's mission and goals to prevent a recurrence of the previous issues.

Remember, the rehiring process should align with your company's bylaws and any relevant legal requirements. Transparency and clear communication throughout the process are crucial to maintain trust among your stakeholders.


Sophisticated evolutionary models are needed to accurately estimated expected mean and variance in genetic distances. For example, rare events of large effect (e.g. recombination) also introduces variation beyond within-strain mutation.


Would work for many using whole genomes. CpG methylation patterns could also work.

"Despite the important role that monozygotic twins have played in genetics research, little is known about their genomic differences. Here we show that monozygotic twins differ on average by 5.2 early developmental mutations and that approximately 15% of monozygotic twins have a substantial number of these early developmental mutations specific to one of them."

https://www.nature.com/articles/s41588-020-00755-1


You may find this pair of articles interesting:

https://www.washingtonpost.com/outlook/we-dont-need-to-save-...

https://www.washingtonpost.com/opinions/2017/12/15/53e6147c-...

Species do go extinct, but not at the rate we are experiencing today. Even if the current rate of species loss was equal to the historical rate, that does not mean that humans wish to live in such a natural state of chaos. Did American culture lose some of its heritage with the near-extinction of the buffalo? Is it any less of a failure of humankind to drive polar bears to extinction than it would be to obliterate the complete works of Jack London from the face of the Earth? That shit is cool, and we should try to preserve it for future generations.


I think species have died at such rates before, during earlier mass extinction events. It's natural they happen once in a while.

If we always preserve what we have, there will be no room for something new to develop.


You realize we're not in a massive extinction event now right? You're comparing things like giant meteors killing all the dinosaurs to right now? If you can see the sun, we shouldn't have all these animals dying.


> You realize we're not in a massive extinction event now right?

We are, in fact, in a mass extinction event right now, with extinction rates estimated at 1-2 orders of magnitude greater than any previous such event.

https://en.m.wikipedia.org/wiki/Holocene_extinction

> If you can see the sun, we shouldn't have all these animals dying.

Not all previous mass extinctions have involved the sun be blotted out by impact or volcanic events, though several have.


Sure. A mass extinction event which will take humans with it. Then a few million years down the line new speciation will fill all of the ecological niches in whatever equilibrium arises. The planet and life themselves are unlikely to be completely wiped out, absent some future technology we can’t yet imagine.

As long as you don’t have any attachment to anything more narrow than “all life on earth” (e.g. your family, language, city, country, culture, species, ...) thriving for a long time into the future, there’s no reason not to just shrug at whatever impending apocalypse.


Interesting wording - I indeed don't have any attachment to the things you mention. I do want intelligent life (for now, humanity) to survive and stay powerful, but I'll take the bet that we're adaptable enough to manage even if 90% of the other species perish.


> I think species have died at such rates before, during earlier mass extinction events.

No, they haven't; extinction rates in the current mass extinction event are much higher than previous ones.


When you put it this way, it makes me realize I'd rather live 400 years while losing three quarters of my waking hours than to live 100 years without any loss of waking hours. Experience centuries, and all that.


Exactly. And just imagine they find fixes for all the age related diseases (basically any organ failure) in the next decades, but not for Alzheimer‘s. You will hate yourself for not just having slept more. Perhaps everybody is then almost guaranteed to turn 125, and you come down with Alzheimer‘s at age 65.



Interesting how the speed readers tended to give short replies with links to tools while the slow readers tended to give longer replies, questioning the premise that learning to speed read is effective for learning. If OP, a speed reader, speed reads poorly, whose advise will s/he follow?


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