I agree. It's really cool. I wonder if this was written with AI assistance. Seems like the perfect kind of fun project that a dev team would really be able to crank out pretty quickly whereas five years ago, there might not have been time or budget for something like this.
It’s a simple math of risk vs reward. Let me explain before dismissing my argument.
Do you know why there are so many “Big Pharma”? It has to be big, because most of the smaller ones simply can’t survive for long. Developing drug is a difficult process. Whopping 90% of compounds fail during the three phase clinical trial period, $40k per patient in the trial, hundreds of millions of dollars per trial.
Every failed trial is a signal for career change for people who develops drugs. You think people will invest in such risky business without expecting a big reward? Asking for low drug price without lowering the clinical trial cost is assuming drugmakers can print money. Unfortunately biology doesn’t work like that.
A lot of us who develop drug are doing it because we believe this is a meaningful thing we can do in the world. They are just hidden behind investors like Shkrelli, who isn’t even anywhere near the actual people who make the drug. But we do need the money to develop the drug. A lot of it.
I hope you understand.
The real solution is to lower the cost of the trial. And I maintain that the drug company isn’t in control of this.
the simple math is these companies spend less than 20% of their revenue on drug development and have operating margins over 40% so prices don't need to be as high as they are
You need to take into account of the fact that patent clock starts ticking as soon as you file it, whether the drug gets approved by the FDA or not. The drug development process itself eats away that exclusivity at about 12 years on average, so that 40% needs to account for the time when you don’t get another drug approved (remember the 90% failure rate).
Drug business is EXTREMELY hard, and investors aren’t running a charity. There needs to be high profit margin to motivate people who fund the discovery and development process for new drugs to come out.
As I keep saying, once we bring down the cost of clinical trial (which is totally artificial, and not under the influence of pharma), you will bring down the risk and cost of drug.
Again, you are pointing the finger at the effect of high medical cost rather than the cause. Ask yourself: why are doctors in US paid 3x the amount compared to UK? Do they raise price because of the drugs? No.
Worth mentioning: I don't believe they have confirmed it was FSD yet. It just says Autopilot which can be the basic one which just keeps you in a lane.
In any case it's frightening that any version of it it wasn't capable of detecting a motorcycle in front of the car and stopping.
It probably was FSD -- FSD is available to pretty much everybody in April, so it seems unlikely he was using Autopilot.
But what seems likely to me is that the driver had his foot on the accelerator. FSD is relatively timid. For example, it will slam on the brakes if it sees a pedestrian that it thinks might cross in front of the car. The driver can press on the accelerator to prevent this. I've gotten used to just keeping my foot on the accelerator for one particular road where FSD is particularly prone to slowing down for no good reason.
It amazes me how people can make snarky comments like this given what's going on in Ukraine. Militaries need to exist precisely so some dictator like Putin can't wake up one day on a whim and be like "you don't deserve to exist; I'm going to take over your country." You can either live in this reality or bask in some imagined smug moral superiority. Your choice.
Good job Weather Channel dev. I just wish it would loop forever. Make a loop checkbox at the start screen.
Also the music slaps.
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