I got pi to write me a very basic sandbox based on an example from the pi github. Added hooks for read/write/edit/bash, some prompts to temp/perm override. Have a look, copy-paste what you like.
Yeah I wrote a small landlock wrapper using go-landlock to sandbox pi that works well (not public, similar projects are landrun and nono).
Note that if you sandbox to literally just the working directly, pi itself wont run since pretty much every linux application needs to be able to read from /usr and /etc
I do this with an extension. I run all bash tools with bwrap and ACLs for the write and edit tools. Serves my purposes. Opens up access to other required directories, at least for git and rust.
I think I published it. Check the pi package page.
Curious how people here are using obsidian when taking notes during meetings in the context of AI note taker. I find myself incapable of using features like links as I'm interacting with say a client. I've found AI note takers to be really powerful to help free my mind during meetings though.
Either someone or I, of course, turn on a Note Taker that can transcribe the meeting notes. That file can go into Obsidian.
Unfortunately, most people don’t refer back to it and would wait for someone to do it as part of the spec or project tasks assigned by the Project Manager.
However, I love taking notes in meetings using graphs, arrows, boxes with text, etc. Sometimes, I use an iPad with the Pencil, but I prefer a pen on Paper. This one is usually the one that gets shared, and people seem to like it for understanding the context or for referring back to what they heard during meetings in a simpler, yet faster/easier way.
My methods are inspired by Dan Roam’s Books. I browse/re-read the books pretty often. https://www.danroam.comhe
Computational biology/cheminformatics has probably been on the most frustrating investments pharma companies have made in the past 20 years. There's been waves of optimism with many hires, then a slump after reality doesn't match optimistic expections, and so on. This time it may actually be different, and I myself am in that camp. I'm particularly excited by the discoveries in sampling methods that aren't just molecular dynamics. And the cellular foundation models for pre-screening drug interactions - they aren't quite there yet, but give it time.
InChI isn't really meant to be used as a format to store 2D molecules say for rendering but rather serves as a unique descriptive chemical identifier. InChI has many flavors but the Standard InChI yields one unique identifier for multiple forms (tautomers) of the same molecule.
TandemAI is an advanced technology company dedicated to reinventing drug discovery infrastructure. The company integrates proprietary AI-driven, high-performance computation with its efficient, large-scale in-house wet lab operations to deliver a turnkey drug discovery solution. We are looking for a Senior Backend Engineer to join our growing Web Applications team. You will actively contribute to back-end initiatives for our cutting-edge computational platform. The candidate, will work to create a state-of-the-art client-facing molecular design web application that seamlessly integrates the TandemAI molecular physics-based computational platform.
Our stack is Java Spring Boot, Python, PostgreSQL, OpenSearch and we use Slurm to manage most our HPC jobs.
If you have a science background and strong engineering skills this could be an exciting opportunity for you!
If you're interested feel free to email me with subject "Hacker News TandemAI" directly at frederick [dot] parsons [at] tandemai [dot] com
This is one of those ghost jobs, the poster keeps posting a job but the job board has been broken all for forever. Someone replied to their prev posting and I even emailed them but received no response.
TandemAI | Backend Software Engineer | Full-time | NYC preferred | Boston/Remote (US, Canada) | https://tandemai.com/ TandemAI is an advanced technology company dedicated to reinventing drug discovery infrastructure. The company integrates proprietary AI-driven, high-performance computation with its efficient, large-scale in-house wet lab operations to deliver a turnkey drug discovery solution.
We are looking for a Senior Backend Engineer to join our growing Web Applications team. You will actively contribute to back-end initiatives for our cutting-edge computational platform. The candidate, will work to create a state-of-the-art client-facing molecular design web application that seamlessly integrates the TandemAI molecular physics-based computational platform.
Our stack is Java Spring Boot, Python, PostgreSQL, OpenSearch and we use Slurm to manage most our HPC jobs.
If you have a science background and strong engineering skills this could be an exciting opportunity for you!
If you're interested feel free to email me with subject "Hacker News TandemAI" directly at frederick [dot] parsons [at] tandemai [dot] com
TandemAI | Backend Software Engineer | Full-time | NYC/Boston/Remote (US, Canada) | https://tandemai.com/
TandemAI is an advanced technology company dedicated to reinventing drug discovery infrastructure. The company integrates proprietary AI-driven, high-performance computation with its efficient, large-scale in-house wet lab operations to deliver a turnkey drug discovery solution.
We are looking for a Senior Backend Engineer to join our growing Web Applications team. You will actively contribute to back-end initiatives for our cutting-edge computational platform. The candidate, will work to create a state-of-the-art client-facing molecular design web application that seamlessly integrates the TandemAI molecular physics-based computational platform.
Our stack is Java Spring Boot, Python, PostgreSQL, OpenSearch and we use Slurm to manage most our HPC jobs.
If you have a science background and strong engineering skills this could be an exciting opportunity for you!
If you're interested feel free to email me with subject "Hacker News TandemAI" directly at frederick [dot] parsons [at] tandemai [dot] com
